HYALINE MEMBRANE DISEASE(HMD)
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작성일 23-01-02 03:52본문
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HYALINE MEMBRANE DISEASE(HMD)
1. Absence of surfactant
-> high surface tension -> tendency to become atelectatic
2. major constituents of surfactant
; dipalmitylphosphatidylcholine(lecithin), phosphatidyl glycerol, apoproteins(SP-A,B,C)
3. factors supressing surfactant synthesis
; asphyxia, hypoxemia, pulmonary ischemia, hypovolemia, hypotension, cold stress
III. PATHOLOGY
생후 6-8hr 이전에는 특징적인 소견 나타나지 않음
1. grossly - deep purplish red and liver like in consistency
2. microscopically - alveolar duct, alveoli and bronchiole
-> lined with acidophylic, homogenous, or granular membrane
IV. CLINICAL MANIFESTATION
- tachypnea, prominent grunting, intercostal and subcostal retraction, nasal flaring, duskiness, cyanosis(unresponsive to oxygen therapy)
-> progressive worsening cyanosis & dyspnea, apnea, irregular respiration, mixed respiratory and metabolic acidosis, edema, ileus, oliguria
- Improvement is heralded by a spontaneous diuresi…(생략(省略))
1. Absence of surfactant -> high surface tension -> tendency to become ate... , HYALINE MEMBRANE DISEASE(HMD)기타레포트 ,
Download : HYALINE MEMBRANE DISEASE(HMD).hwp( 23 )
-> high surface tension -> tendency to become ate...
설명
1. Absence of surfactant
,기타,레포트
순서
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레포트/기타
다.